Nivolumab injection Online | Opdyta cost | Apple pharmaceuticals
DESCRIPTION Nivolumab is a prescription drug which is used under the supervision of a doctor Nivolumab belongs to a human monoclonal antibody which stops the interaction between PD-1 and its ligands, PD-L1 and PD-L2. Nivolumab is an IgG4 kappa immunoglobulin which has a calculated molecular mass of 146 kDa. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line. Nivolumab is also known as an immune checkpoint inhibitor. Sometimes these drugs are called targeted therapies because they target specific proteins (receptors) on the surface of cells. INDICATION Nivolumab is indicated for the treatment of patients having : • Melanoma • Non-Small Cell Lung Cancer • Kidney (Renal Cell) Cancer MECHANISM Binding of these ligands to the PD-1 receptor occur on T cells, prohibits T cell multiplication and cytokine production. Upregulation of the PD-1 ligands occurs in some tumor and signaling via this pathway can provide to the prohibition of active T-cell im...