Evertor 5mg tablet - Everolimus | Myapplepharma

Description

Evertor 5mg belongs to class of anti-cancer drugs Evertor5mg contains of an active compound known as Everolimus which interferes with the development of cancer cell and the process is slowed down. Evertor 5mg tablets is not a curable medication, which helps to slow their spreading into the body.

Prescribed For

The drug Evertor 5mg is mainly used for the treatment of following disease
• kidney carcinoma
• Breast carcinoma
• Brain carcinoma
Evertor 5mg is also used to treat in various advanced stage cancer in stomach, intestines or pancreas.

Mechanism

Everolimus is a prohibition of mTOR, links at peak compatibility to FK506 binding protein 12, through producing drug complex which prevents the productive of mTOR. This inhibition reduces the activity of effectors downstream, which may lead to stoppage of cell progression from G1 into S phase, finally causes cell growth arrest and apoptosis.

Dosage

Evertor 5mg tablets should be given with or without food. The dosage regimen of Evertor; In breast cancer, renal cell cancer, pancreatic cancer, Neuroendocrine cancer: The prescribed dosage is 10mg should be taken as a single dose. In Brain or intracranial cancer: The prescribed dosage of Evertor as a single dose. is 4.5mg/m2 given orally In pediatric: The pediatric dosage of Evertor as a single dose in brain or intracranial tumor is 4.5mg/m2 should be given orally.

Drug-Drug interaction

Interaction of Evertor 5mg with a strong inhibitor of CYP3A4, or P-gp, cause reducing the efflux of Everolimus and high plasma concentration of Everolimus. Concomitant use of Evertor 5mg with strong CYP3A4 inducers will be increasing the disclosure of Everolimus. Interaction of Evertor 5mg with cyclosporine will be increasing the AUC level of Everolimus frequently.

Side Effects

• Nephrotoxicity
• Thrombocytopenia
• Hypersensitivity reactions
• Hyperlipemia
• Angioedema
• Lymphomas & other malignancy
• Male infertility
• Proteinuria

Overdosage

The over dosage of Everolimus is limited If overdosage occurs patient must be provided with supportive measures. And monitor evidence of toxicity in Everolimus overdosage

Missed Dose

If the patients missed the dose, patients must consult with the medical practitioner and follow the instructions given by them. Or missed dose should be avoided and follow the regular dosing schedule.

FOR MORE INFORMATION

EMAIL:


applepharmaceutical@gmail.com

PHONE:


91- 9987711567

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